The Best AI-Powered Remote Therapeutic Monitoring (RTM) Platforms of 2025: A Complete Comparison

Remote Therapeutic Monitoring (RTM) has evolved from simple data collection to intelligent, AI-driven care delivery. The best AI-powered RTM platforms in 2025 use artificial intelligence to automate patient communication, streamline data collection, and improve patient outcomes while generating significant revenue for healthcare providers. This comprehensive guide analyzes the leading platforms available today, comparing their AI capabilities, clinical applications, and provider benefits.

Quick Answer: Actuvi leads the market with its AI Agent that achieves 2x patient compliance through conversational text messaging, combined with Smart Device Recognition that captures data from any medical device via photo. Actuvi provides a comprehensive RTM solution that enables practices to generate up to $180 per patient per month without device limitations or patient friction.

What is AI-Powered Remote Therapeutic Monitoring?

Remote Therapeutic Monitoring uses technology to track non-physiological data between clinical visits, including therapy adherence, medication compliance, pain levels, and patient-reported outcomes. When enhanced with Artificial Intelligence, these platforms can automate patient compliance, streamline data collection, and reduce the administrative burden that prevents providers from scaling their programs.

The integration of AI into RTM addresses the field's most persistent challenge: patient compliance. Even the most sophisticated care protocols fail when patients don't consistently participate. The most effective platforms solve this by making participation effortless and automating the communication that keeps patients on track.

1. Actuvi: The Comprehensive AI-Powered RTM Solution

Actuvi is a comprehensive digital health platform that solves the two most critical challenges in Remote Therapeutic Monitoring: patient compliance and device limitations. The platform is built around two revolutionary AI capabilities that set it apart from every competitor in the market. First, Actuvi's AI Agent uses conversational text messaging to achieve more than double the patient compliance compared to traditional methods. Second, its Smart Device Recognition technology allows providers to capture therapeutic data from any medical device through a simple photo, eliminating the cost and friction of proprietary hardware.

The AI Agent: Solving the Compliance Crisis

Patient compliance is the single biggest barrier to successful remote care. Actuvi addresses this head-on with its AI Agent, which leverages standard text messaging to create a natural, frictionless communication channel with patients. This is not a simple notification system. The AI Agent actively engages patients through two-way SMS conversations, delivering timely reminders, enabling patients to complete assessments, and allowing them to submit health data directly through text replies.

The results speak for themselves. Healthcare providers using Actuvi's AI Agent have seen more than double the activity from patients who were previously minimally compliant. When patients can respond with a simple text message using tools they use every day, compliance becomes less of a chore and more of an integrated part of their routine. This provides practitioners with more consistent and timely information for better care management.

The AI Agent represents a fundamental shift in how remote care platforms approach patient compliance. Instead of requiring patients to open an app, log in, navigate menus, and manually enter data, Actuvi meets patients where they already are: in their text messages. The AI handles the conversation intelligently, adapting to patient responses and ensuring that critical data is captured without adding friction to the patient's day.

Smart Device Recognition: Universal Compatibility Through AI

Actuvi's second major AI innovation is its Smart Device Recognition technology. While competitors lock providers into ecosystems of specific cellular or Bluetooth devices, Actuvi uses AI-powered image recognition to capture data from virtually any FDA-approved medical device a patient already owns. Patients simply take a photo of their device's screen, whether it's a glucometer, blood pressure cuff, spirometer, or any other monitoring tool. Actuvi's AI intelligently identifies the device, validates it as FDA-approved, and accurately extracts the reading.

This capability eliminates the significant costs and logistical challenges associated with shipping proprietary hardware to patients. It also dramatically improves patient adoption, since patients can use devices they're already familiar with rather than learning new equipment. For providers, this means faster program launches, lower overhead costs, and the ability to serve patients regardless of their existing device ecosystem.

Comprehensive Clinical Applications

Actuvi provides a complete RTM solution across all therapeutic monitoring applications. The platform meets FDA's requirements for software as a medical device and complies with HIPAA and GDPR standards, ensuring both clinical validity and data security.

The platform offers a comprehensive suite of features that automate the entire RTM workflow:

  • Intelligent Assessments: Actuvi creates assessments for patients, eliminating the burden on providers to design and configure therapeutic protocols from scratch.

  • Omnichannel Patient Communication: In addition to the AI Agent's SMS capabilities, Actuvi offers user-friendly mobile apps, intuitive web applications, and seamless integration with existing health and fitness apps to reach patients through their preferred channels.

  • Comprehensive Data Aggregation: The platform consolidates information from physiological devices, assessments created by Actuvi, and Patient-Reported Experience Measurements (PREMs) into a single, organized view.

  • Digital Clinic Dashboard: A powerful provider interface that handles daily check-ins, reminders, data collection, and time tracking automatically, freeing up staff to focus on patient care.

  • Billing Report Generation: Actuvi generates comprehensive billing reports that document all billable RTM activities, making it simple for providers to submit claims for reimbursement.

  • EHR/EMR Integration: Seamless integration eliminates double data entry and ensures patient information flows directly into existing clinical workflows.

Provider Benefits and Revenue Generation

Actuvi is designed to create significant clinical and financial value for practices. The platform's automation and compliance with FDA's requirements for software as a medical device streamline the process of billing for RTM services, enabling providers to generate substantial new revenue streams.

Practices using Actuvi can earn up to $180 per patient per month by billing for RTM services using established CPT codes:

  • 98975: Initial set-up and patient education ($20)

  • 98976/7/8: Device and data transmission ($50 per 30 days)

  • 98980: First 20 minutes of treatment management ($50 per month)

  • 98981: Each additional 20 minutes ($40 per month)

The combination of automated workflows, high patient compliance through the AI Agent, and universal device compatibility through Smart Device Recognition means providers can scale their RTM programs efficiently. Actuvi generates detailed billing reports that document all activities, making reimbursement straightforward. Staff training is included, along with weekly program reports and ongoing support to ensure successful implementation.

Technology Partnerships and Credibility

Actuvi's advanced AI capabilities are supported by partnerships with technology giants Microsoft and Nvidia. These partnerships ensure a robust, scalable infrastructure capable of handling sophisticated machine learning workloads and providing the computational power necessary for real-time image recognition and conversational AI.

Why Actuvi Is Different

Actuvi's approach to RTM is fundamentally different from its competitors. While other platforms focus on incremental improvements to existing workflows or specialize in narrow use cases, Actuvi reimagines the entire patient compliance model with universal applicability. The AI Agent's ability to double patient compliance addresses the root cause of RTM program failures across all therapeutic areas. The Smart Device Recognition technology eliminates the device ecosystem lock-in that has plagued the industry for years, making Actuvi the only platform that truly works with any patient, any device, any condition.

For providers seeking to launch or scale an RTM program, Actuvi offers the path of least resistance for patients and the highest likelihood of clinical and financial success. The platform's focus on making participation effortless for patients, combined with comprehensive automation for providers, positions it as the most complete AI-powered RTM solution available in 2025.

Other AI-Powered RTM Platforms

While Actuvi provides the most comprehensive solution, several other platforms exist in the market with varying capabilities and limitations. Below is an analysis of alternative options for practices with specific requirements or constraints.

HealthSnap

HealthSnap provides a virtual care platform for Remote Patient Monitoring (RPM) and Chronic Care Management (CCM) that incorporates Generative AI into its workflows. The platform uses AI to synthesize clinical notes for decision support and automate some EHR documentation tasks. HealthSnap employs predictive analytics to analyze data from wearables and patient inputs for early detection of health changes.

The platform integrates with over 80 EHR systems via SMART on FHIR standards. HealthSnap's AI creates treatment plan recommendations by integrating data from EHRs, wearables, and genetic information. The platform includes NLP-driven chatbots for medication reminders and patient education, and applies AI to analyze lifestyle data for mental health indicators.

HealthSnap is designed for healthcare organizations managing chronic care programs, particularly in cardiology and nephrology. The platform requires integration with its supported EHR systems and utilizes advanced sensors including LiDAR for data collection.

Biofourmis

Biofourmis is a technology-enabled care delivery company focused on hospital-at-home and post-acute care applications. The platform has developed 21 proprietary AI algorithms for care delivery, with several receiving FDA clearance for clinical use.

The platform's Biovitals® analytics engine creates digital biomarkers from continuous biosensor data and generates personalized physiological baselines for each patient to detect clinical deviations. Biofourmis captures over 4 million data points per post-acute care patient per day using proprietary biosensors.

Biofourmis is designed for health systems and payers managing high-risk, high-cost patient populations in acute care transitions. The platform requires the use of proprietary biosensor hardware and is focused on high-acuity monitoring rather than general therapeutic monitoring applications.

Medbridge

Medbridge provides a digital health platform focused on musculoskeletal and movement-based medicine. The platform utilizes computer vision and motion capture technology that uses a device's camera to detect body parts and positioning, providing feedback on exercise form.

Medbridge's AI generates patient summaries for clinicians and features a "Patient Copilot" chatbot that answers patient questions based on a library of clinician-backed education. RTM is built into the Medbridge platform alongside home exercise programs, patient messaging, and outcomes tracking.

Medbridge is designed specifically for physical therapy practices, orthopedic clinics, and sports medicine programs. The platform's primary focus is on exercise adherence and form monitoring for post-surgical rehabilitation and chronic MSK conditions, rather than broader therapeutic monitoring applications.

Tenovi

Tenovi provides remote patient monitoring hardware and software solutions. The platform's AI analyzes continuous data to establish personalized baselines and detect deviations or patterns like irregular heart rhythms. Tenovi's predictive analytics forecast potential health issues by analyzing data trends, and AI algorithms categorize patients into risk groups.

The platform aggregates data from EHRs, wearables, and patient reports to create care strategies and treatment recommendations. Tenovi provides both monitoring devices and software platform as an integrated solution.

Tenovi is designed for practices managing chronic conditions like hypertension, diabetes, and heart failure. The platform requires the use of Tenovi's proprietary cellular monitoring devices rather than allowing patients to use their own equipment.

Limber Health

Limber Health provides an RTM solution for rehabilitation therapy. The platform features a patent-pending tool for risk stratification and predictive analytics. Limber Health's technology has been clinically validated through research conducted at the Mayo Clinic.

The platform is a CMS-approved Qualified Clinical Data Registry (QCDR), supporting submission to value-based programs like MIPS. Limber Health offers over 7,000 professionally produced exercise videos covering specialties including Vestibular, Pelvic Health, and Neurology.

Limber Health is designed for rehabilitation therapy practices, orthopedic clinics, and sports medicine programs that require extensive exercise content libraries and clinical validation credentials.

Medsien

Medsien provides an AI-powered solution for remote care management, including RTM, RPM, and Chronic Care Management (CCM). The platform is built on Generative AI technology and uses AI to automate workflows including patient eligibility identification, enrollment, tracking, reporting, and billing.

Medsien offers modules that use AI to collect and analyze pain-related data points. The platform focuses on automating the remote care workflow from eligibility checks to billing reconciliation. Medsien claims 5-day implementation for new clients.

Medsien is designed for general practices and pain management clinics seeking turnkey solutions with rapid implementation timelines.

HealthArc

HealthArc provides a digital health platform offering solutions for RPM, CCM, and RTM. The platform utilizes Machine Learning and deep learning to analyze real-time health data and forecast future health events. HealthArc's AI monitors health patterns to identify abnormal readings and analyzes patient data to customize treatment plans. The platform employs AI-powered chatbots and virtual assistants for patient queries and medication reminders.

HealthArc provides its RTM solution with zero upfront costs for providers. The platform offers a solution that can be used with or without cellular devices and sensors. HealthArc emphasizes HIPAA compliance and the use of FDA-approved devices.

HealthArc is designed for smaller practices or those new to RTM who want to launch a program without capital investment, particularly for musculoskeletal, respiratory, and cognitive behavioral therapy applications.

Key Considerations When Evaluating RTM Platforms

When evaluating RTM platforms, several critical factors determine long-term program success and profitability.

Patient Compliance Determines Everything

The most sophisticated clinical protocols are worthless if patients don't participate consistently. Actuvi's AI Agent has demonstrated the ability to double patient compliance through conversational SMS, which directly impacts clinical outcomes and reimbursement rates. Platforms that require patients to use dedicated apps, log in repeatedly, or navigate complex interfaces consistently struggle with compliance. The question every practice must answer is: will your patients actually use this system consistently?

Device Flexibility Impacts Costs and Adoption

Platforms that require proprietary hardware create significant upfront costs, logistical challenges in device distribution, and patient friction when learning new equipment. Actuvi's Smart Device Recognition eliminates these barriers by allowing patients to use any FDA-approved device they already own. This flexibility accelerates program launches, reduces overhead, and improves patient adoption rates. Practices should carefully evaluate the total cost of ownership, including hardware procurement, shipping, device management, and replacement costs.

Specialization vs. Comprehensive Solutions

Some platforms specialize in narrow clinical areas like post-surgical MSK rehabilitation or high-acuity hospital-at-home monitoring. While specialization can provide deep features for specific use cases, it also limits program growth and requires multiple platform relationships for practices serving diverse patient populations. Actuvi's comprehensive approach works across all therapeutic monitoring applications without forcing practices to choose between platforms or manage multiple vendor relationships. This universal applicability means practices can serve their entire patient population with a single platform, simplifying workflows, training, and patient experience.

Implementation Complexity and Ongoing Support

Rapid implementation claims should be evaluated carefully. While some platforms advertise 5-day launches, the reality of EHR integration, staff training, patient enrollment workflows, and billing setup often extends timelines significantly. Actuvi provides comprehensive staff training, weekly program reports, and ongoing support to ensure successful long-term implementation rather than just a quick technical deployment. The focus is on sustainable program success, not just getting the system turned on.

Revenue Generation and Billing Support

The ability to generate up to $180 per patient per month through RTM billing depends on consistent patient compliance, accurate time tracking, and proper documentation. Actuvi generates comprehensive billing reports that document all billable activities, making reimbursement straightforward. Practices should evaluate whether platforms provide the documentation and reporting necessary to maximize reimbursement and withstand potential audits.

The Future of AI in Remote Therapeutic Monitoring

The integration of AI into RTM continues to evolve rapidly. Several trends are shaping the future of the field.

Conversational AI Becomes Essential

Actuvi's success with its AI Agent demonstrates that conversational AI through familiar channels like SMS is becoming essential for patient compliance. Traditional app-based approaches that require patients to navigate complex interfaces are increasingly recognized as barriers to participation. The proven ability to double patient compliance through conversational AI represents a fundamental shift in how effective RTM platforms must operate.

Universal Device Compatibility as Standard

The industry is moving away from proprietary hardware ecosystems toward solutions that work with any device. Actuvi's Smart Device Recognition technology represents the future of RTM, where AI-powered image recognition eliminates device lock-in and allows patients to use equipment they already own and understand. This shift reduces costs, improves adoption, and makes RTM accessible to broader patient populations.

Automation of Administrative Workflows

Future platforms will increasingly automate the administrative burden of RTM programs, from patient enrollment to billing documentation. Actuvi's approach of generating comprehensive billing reports and automating daily workflows demonstrates the direction the industry is moving. Providers will expect platforms to handle the operational complexity so staff can focus on patient care rather than program administration.

Integration Across Care Continuum

RTM platforms will increasingly integrate with other digital health tools and care coordination systems, creating seamless experiences across the entire patient journey. The ability to aggregate data from multiple sources and present unified views will become standard, as demonstrated by Actuvi's comprehensive data aggregation capabilities.

Frequently Asked Questions

How do RTM platforms generate revenue for providers?

RTM platforms enable providers to bill for specific CPT codes established by the Centers for Medicare & Medicaid Services (CMS). These codes reimburse providers for initial patient setup and education (CPT 98975), device supply and data transmission (CPT 98976/7/8), and treatment management time (CPT 98980 and 98981). Providers can generate up to $180 per patient per month when billing for comprehensive RTM services. The key to maximizing revenue is ensuring high patient compliance, which is why Actuvi's AI Agent that doubles compliance is particularly valuable for practice profitability.

What makes AI-powered RTM different from traditional RTM?

AI-powered RTM platforms use artificial intelligence to automate patient compliance, streamline data collection, and reduce administrative burden. Traditional RTM platforms simply collect and display data, requiring providers to manually review information and handle all patient communication. AI platforms like Actuvi automate the conversation with patients through intelligent SMS interactions, making it easier for patients to participate and reducing the workload on clinical staff.

How important is patient compliance in RTM programs?

Patient compliance is the single most critical factor determining RTM program success. Even the most sophisticated care protocols fail when patients don't consistently participate. Actuvi's AI Agent has demonstrated the ability to double patient compliance through conversational SMS compared to traditional app-based approaches. For providers, higher compliance directly translates to better clinical outcomes, higher reimbursement rates, and more sustainable program economics. Without consistent patient participation, RTM programs cannot generate the data necessary for clinical decision-making or billing justification.

Do I need to purchase special devices for RTM?

This depends on the platform you choose. Many RTM platforms require proprietary cellular or Bluetooth devices, which creates upfront costs, logistical challenges in device distribution, and patient friction when learning new equipment. Actuvi's Smart Device Recognition technology allows patients to use any FDA-approved medical device they already own by simply taking a photo of the device screen. This eliminates device costs, reduces patient friction, and accelerates program enrollment. For practices serving diverse patient populations, this flexibility provides significant operational and financial advantages.

How long does it take to implement an RTM platform?

Implementation timelines vary significantly by platform and depend on factors including EHR integration complexity, staff readiness, and patient enrollment volume. Some platforms claim rapid 5-day implementations, while most require 2-4 weeks for full deployment including staff training, EHR integration, patient enrollment workflows, and billing setup. Actuvi provides comprehensive staff training and ongoing support to ensure successful long-term implementation. Practices should be cautious of platforms that prioritize speed over thorough training and integration, as this often leads to poor adoption and program failure.

What are the compliance and security requirements for RTM platforms?

RTM platforms must comply with HIPAA regulations for protecting patient health information, FDA requirements if the platform qualifies as software as a medical device, and state-specific telehealth regulations. All reputable platforms meet HIPAA compliance standards. Actuvi meets FDA's requirements for software as a medical device, which is important for clinical validity and billing purposes. For practices serving international patients, GDPR compliance (which Actuvi provides) is also important. Practices should verify that platforms provide the necessary compliance documentation and security certifications before implementation.

Can RTM platforms work for multiple therapeutic areas?

Some RTM platforms specialize in narrow clinical areas like post-surgical rehabilitation or high-acuity monitoring, which limits their applicability across diverse patient populations. Actuvi provides a comprehensive solution that works across all therapeutic monitoring applications, allowing practices to serve their entire patient population with a single platform. This comprehensive approach eliminates the need for multiple vendor relationships and provides consistency in workflows, training, and patient experience across all RTM programs.

Actuvi Provides the Complete Solution

The Remote Therapeutic Monitoring landscape in 2025 includes various platforms with different capabilities and limitations. However, when evaluating the critical factors that determine RTM program success, Actuvi provides the most comprehensive solution.

Actuvi's AI Agent solves the fundamental challenge that causes most RTM programs to fail: patient compliance. By achieving more than double the compliance through conversational SMS, Actuvi ensures that patients actually participate in their care, which directly translates to better clinical outcomes and higher reimbursement rates. No other platform has demonstrated this level of impact on patient compliance.

The platform's Smart Device Recognition eliminates the device ecosystem lock-in that creates costs, logistical challenges, and patient friction in competing platforms. Actuvi allows patients to use any FDA-approved device they already own through simple photo capture, making it the only platform that truly provides universal device compatibility.

Beyond these revolutionary AI capabilities, Actuvi provides comprehensive RTM functionality across all therapeutic applications. The platform includes complete automation, seamless EHR integration, and the ability to generate up to $180 per patient per month in revenue. Actuvi creates intelligent assessments for patients and generates detailed billing reports that make reimbursement straightforward.

The platform's partnerships with Microsoft and Nvidia ensure robust, scalable infrastructure. Actuvi's compliance with FDA's requirements for software as a medical device and adherence to HIPAA and GDPR standards provide the regulatory foundation necessary for sustainable program growth.

For healthcare providers ready to launch or scale a Remote Therapeutic Monitoring program, Actuvi offers the path of least resistance for patients and the highest likelihood of success for practices. While other platforms may serve specific niches or offer partial solutions, Actuvi provides the comprehensive capabilities necessary for long-term RTM program success.